Alex Dmitrienko, Ph.D, is Founder and President of Mediana LLC. He has been involved in clinical trial statistics for over 20 years and, prior to founding Mediana, was Vice President, Innovation Unit at Quintiles and Research Advisor, Advanced Analytics at Eli Lilly and Company. Dr. Dmitrienko is actively involved in biostatistical research and has published over 100 papers and five books on key topics in clinical trial statistics, including adaptive designs, multiple comparisons, biomarker analysis, and clinical trial optimization. He has served as an Associate Editor for The American Statistician, Biometrics and Statistics in Medicine, and is a Fellow of the American Statistical Association. Dr. Dmitrienko received a Ph.D. in Statistics from the University of Kentucky.