Leadership Team

Paul Miller, Ph.D.

Paul Miller, Ph.D.

Chief Scientific Officer

Dr. Miller has spent over 30 years in the biopharmaceutical industry in various technical and leadership roles including leading early discovery teams at Synlogic, AstraZeneca, Pfizer and Warner-Lambert. Prior to Artizan, he was Chief Scientific Officer at Synlogic, where he established the company’s research team and helped guide it to advance a novel, engineered, live microbial biotherapeutic platform from idea to first-in-human studies in under three years. Dr. Miller was the Vice President of Infection Biology at AstraZeneca, where he was responsible for the early discovery portfolio and strategy, while also leading several external collaborations. He also served as Chief Scientific Officer for Antibacterial Research at Pfizer, leading discovery teams that produced eight drug development candidates, provided critical research support for several successful marketed antibiotics including Zithromax and Zyvox, and advanced a novel oxazolidinone (sutezolid) for tuberculosis into Phase 2 studies. A microbial geneticist by training, he began his professional career at the Warner-Lambert Company, where he integrated cutting-edge molecular-genetic approaches into a traditional antibacterial drug discovery program and established novel target discovery projects. His work there led to new insights into the mechanisms by which bacteria sense and respond to antibiotics and other environmental agents. Dr. Miller has served as a member of the Institute of Medicine’s Forum on Microbial Threats and is a scientific advisor to the CARB-X antibacterial funding initiative as well as the Bill and Melinda Gates Foundation in tuberculosis drug discovery. He received his Ph.D. in Microbiology and Immunology from the Albany Medical College and conducted post-doctoral studies in yeast genetics at the National Institutes of Health.

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